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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: C6orf165 All Species: 17.88
Human Site: S516 Identified Species: 35.76
UniProt: Q8IYR0 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IYR0 NP_849145.1 622 71193 S516 P I T K C E S S T Q T N T H I
Chimpanzee Pan troglodytes XP_001154333 622 71118 S516 P I T K C E S S T Q T D T H I
Rhesus Macaque Macaca mulatta XP_001089007 675 76753 S569 P I T K C E S S T Q T D T H I
Dog Lupus familis XP_532227 634 72396 S528 P I T K C E S S T Q T D T H I
Cat Felis silvestris
Mouse Mus musculus Q6PE87 622 70927 G516 P I T K C D N G T Q T D T H I
Rat Rattus norvegicus A1A5Q4 622 70816 G516 P I T K C E N G T Q T D T H I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513345 621 70882 S516 P F T R C D S S S Q T D T H I
Chicken Gallus gallus XP_419848 621 70424 G515 P T T K C D S G S Q T D T H I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2RV06 624 69885 L512 G M P S G Q K L L L K S I S K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611498 576 66763 N478 F R K V V F N N A N L A L L F
Honey Bee Apis mellifera XP_394079 485 56983 C387 E G P E L K M C N H R M V Q T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_780272 623 70581 G517 P I T K C D M G I Q T E V H P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 86.8 84.8 N.A. 79.9 80.5 N.A. 71.3 58 N.A. 48.4 N.A. 20.7 29.1 N.A. 58.4
Protein Similarity: 100 99.8 87.1 90.8 N.A. 90 90.6 N.A. 85.3 76.6 N.A. 67.1 N.A. 40.1 48.5 N.A. 77.2
P-Site Identity: 100 93.3 93.3 93.3 N.A. 73.3 80 N.A. 66.6 66.6 N.A. 0 N.A. 0 0 N.A. 53.3
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 93.3 86.6 N.A. 20 N.A. 13.3 13.3 N.A. 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 9 0 0 9 0 0 0 % A
% Cys: 0 0 0 0 75 0 0 9 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 34 0 0 0 0 0 59 0 0 0 % D
% Glu: 9 0 0 9 0 42 0 0 0 0 0 9 0 0 0 % E
% Phe: 9 9 0 0 0 9 0 0 0 0 0 0 0 0 9 % F
% Gly: 9 9 0 0 9 0 0 34 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 9 0 0 0 75 0 % H
% Ile: 0 59 0 0 0 0 0 0 9 0 0 0 9 0 67 % I
% Lys: 0 0 9 67 0 9 9 0 0 0 9 0 0 0 9 % K
% Leu: 0 0 0 0 9 0 0 9 9 9 9 0 9 9 0 % L
% Met: 0 9 0 0 0 0 17 0 0 0 0 9 0 0 0 % M
% Asn: 0 0 0 0 0 0 25 9 9 9 0 9 0 0 0 % N
% Pro: 75 0 17 0 0 0 0 0 0 0 0 0 0 0 9 % P
% Gln: 0 0 0 0 0 9 0 0 0 75 0 0 0 9 0 % Q
% Arg: 0 9 0 9 0 0 0 0 0 0 9 0 0 0 0 % R
% Ser: 0 0 0 9 0 0 50 42 17 0 0 9 0 9 0 % S
% Thr: 0 9 75 0 0 0 0 0 50 0 75 0 67 0 9 % T
% Val: 0 0 0 9 9 0 0 0 0 0 0 0 17 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _